An archaic HLA class I receptor allele diversifies natural killer cell-driven immunity in First Nations peoples of Oceania
Cell. 2024 Oct 25:S0092-8674(24)01153-X.
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Image: Camilla Faoro
Structure of a fully assembled γδ T cell antigen receptor
Nature. 634, 729–736 (2024)
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Artwork: Ben Gully
Lipidomic scanning of self-lipids identifies headless antigens for natural killer T cells
Proc Natl Acad Sci USA. 2024 Aug 20. 121(34):e232168612
Image: Praveena Thirunavukkarasu
The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4
Nature Commun. 2024 July 23. 15(1):6201
Image: Tiing Jen Loh
A structural basis of T cell cross-reactivity to native and spliced self-antigens presented by HLA-DQ8
JBC. 2024 July 27. 300(9):107612
Image: Mai Tran
Advancing accessible science for low-vision and diverse-needs communities
Cell. 2024 Jul 11;187(14):3496-3501
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Image: Carla Gottgens
Access all areas: multisensory science exhibitions tailored toward blind, low-vision and diverse-needs communities
Immunol Cell Biol. 2024 May-Jun;102(5):321-325
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CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms
Cell. 2023 Oct 12;186(21):4583-4596
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Artwork: Erica Tandori
CD4+ T cell-mediated recognition of a conserved cholesterol-dependent cytolysin epitope generates broad antibacterial immunity
Immunity. 2023 May 9;56(5):1082-1097.e6
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Artwork: Erica Tandori
SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans
Cell 185, 1–11. February 17, 2022.
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Repeated Plasmodium falciparum infection in humans drives the clonal expansion of an adaptive γδ T cell repertoire
Sci Transl Med. 2021 Dec;13(622):eabe7430.
Artwork: Erica Tandori
Recognition of the antigen-presenting molecule MR1 by a Vδ3+ γδ T cell receptor
Proc Natl Acad Sci U S A. 2021 Dec 7; 118(49):e2110288118
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Artwork: Erica Tandori
A natural product compound inhibits coronaviral replication in vitro by binding to the conserved Nsp9 SARS-CoV-2 protein
J Biol Chem. 2021 Oct 28:101362.
Artwork: Erica Tandori
Host immunomodulatory lipids created by symbionts from dietary amino acids
Nature (2021). Published 10 Nov 2021
Full-text access to view only version of paper via SharedIt
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Artwork: Erica Tandori
Binding of a pyrimidine RNA base-mimic to SARS-CoV-2 non-structural protein 9
J Biol Chem. 2021 Jul 28:101018.
Image: Dene Littler
Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein
J Biol Chem. 2021 Aug 9:101065
Image: Priyanka Chaurasia
CD1a selectively captures endogenous cellular lipids that broadly block T cell response
May 7, 2021
J Exp Med (2021) 218 (7): e20202699
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Artwork: Erica Tandori
The molecular assembly of the marsupial γμ T cell receptor defines a third T cell lineage
Science 2021, 371(6536),1383-1388
DOI: 10.1126/science.abe7070
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Artwork: Erica Tandori
The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR
Science Immunology 16 Apr 2021:
Vol. 6, Issue 58, eabe0896
DOI: 10.1126/sciimmunol.abe0896
Summary. Abstract. TOC. Full text.
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Artwork: Erica Tandori
Canonical T cell receptor docking on peptide–MHC is essential for T cell signaling
Science 04 Jun 2021:
Vol. 372, Issue 6546, eabe9124
DOI: 10.1126/science.abe9124
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Artwork: Erica Tandori
Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C
Nat Commun 12,2173 (2021).
https://doi.org/10.1038/s41467-021-22359-x
The molecular basis underpinning the potency and specificity of MAIT cell antigens
Nat Immunol. 2020;10.1038/s41590-020-0616-6.
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Artwork: Erica Tandori
Obituary: Katharina Gaus 1972–2021
Nat Immunol (2021).
https://doi.org/10.1038/s41590-021-00915-30
Image courtesy of ARC Centre of Excellence in Advanced Molecular Imaging
Human T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products.
Sci Immunol. 2020 Jan 3;5(43). pii: eaax5430.
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Artwork: Erica Tandori
A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response
Nature Cancer (2020). DOI: 10.1038/s43018-020-00111-6
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Artwork: Erica Tandori
T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease.
Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1
Sci Immunol. 2020;5(49):eabc9492.
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Artwork: Erica Tandori
A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1.
Science. 2019;366(6472):1522-1527.
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Artwork: Erica Tandori
Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Nature. 2017 May 11;545(7653):243-247.
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Artwork: Vanette Tran
CD4+ T cell-mediated HLA class II cross-restriction in HIV controllers.
A Viral Immunoevasin Controls Innate Immunity by Targeting the Prototypical Natural Killer Cell Receptor Family.
Cell. 2017;169(1):58-71.e14.
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Artwork: Vanette Tran
Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells.
Nat Immunol. 2017 Apr;18(4):402-411.
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Artwork: Vanette Tran