Rossjohn Laboratory

Understanding immune function and dysfunction.

Publication Highlights

Canonical T cell receptor docking on peptide–MHC is essential for T cell signaling

Science  04 Jun 2021:
Vol. 372, Issue 6546, eabe9124
DOI: 10.1126/science.abe9124

Abstract.

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Artwork: Erica Tandori

The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR

Science Immunology  16 Apr 2021:
Vol. 6, Issue 58, eabe0896
DOI: 10.1126/sciimmunol.abe0896

Summary.   AbstractTOC.   Full text.

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Artwork: Erica Tandori

Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C

Nat Commun 12,2173 (2021).

https://doi.org/10.1038/s41467-021-22359-x

Abstract.    Full text.

Obituary: Katharina Gaus 1972–2021

Nat Immunol (2021).

https://doi.org/10.1038/s41590-021-00915-30

Full text.

Image courtesy of ARC Centre of Excellence in Advanced Molecular Imaging

The molecular assembly of the marsupial γμ T cell receptor defines a third T cell lineage

Science  2021, 371(6536),1383-1388
DOI: 10.1126/science.abe7070

Abstract.    Full textReprint.

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Artwork: Erica Tandori

T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease.

Nat Struct Mol Biol. 2020 Jan;27(1):49-61
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Artwork: Erica Tandori

The molecular basis underpinning the potency and specificity of MAIT cell antigens

Nat Immunol. 2020;10.1038/s41590-020-0616-6.

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Artwork: Erica Tandori

Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.

Nature. 2017 May 11;545(7653):243-247. 

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Artwork: Vanette Tran

CD4+ T cell-mediated HLA class II cross-restriction in HIV controllers.

Sci Immunol. 2018 Jun 8;3(24). 
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Artwork: Vanette Tran

Recent Publications